Gunzer, F., Rudolph, W.W., Bunk, B., Schober, I., Peters, S., Müller, T., Oberheitmann, B. and Schröttner, P. (2018) Whole-genome sequencing of a large collection of Myroides odoratimimus and Myroides odoratus isolates and antimicrobial susceptibility studies. Emerging Microbes & Infections, 7 (1). pp. 1-8. DOI https://doi.org/10.1038/s41426-018-0061-x.

Text Peters et al 2018.pdf - Published Version Restricted to Registered users only Available under License Creative Commons: Attribution 4.0. Download (719kB)

Abstract

The genus Myroides comprises several species of Gram-negative, non-motile, and non-fermenting bacteria, which have been regarded as non-pathogenic for decades. Multiple recent reports, however, underscore the pathogenic potential that Myroides sp. possesses for humans. These bacteria seem to be resistant to a wide range of antibiotics (including ß-lactams and aminoglycosides). Therefore, treatment options are limited. Knowledge of antimicrobial resistance, however, is based on only one meaningful comprehensive study and on data published from case reports. This lack of data motivated us to test 59 strains from our Myroides collection (43 M. odoratimimus and 16 M. odoratus) for resistance against 20 commonly used antibiotics. We also performed molecular analyses to reveal whether our bacteria harbor the genus-specific M. odoratimimus metallo-ß-lactamase (MUS-1) or the M. odoratus metallo ß-lactamase (TUS-1), and other ß-lactamases, which may provide an explanation for the extended antimicrobial resistance.

Document Type:	Article
Programme Area:	UNSPECIFIED
Research affiliation:	Infrastructure > Biology Laboratory
Refereed:	Yes
Open Access Journal?:	No
DOI:	https://doi.org/10.1038/s41426-018-0061-x
ISSN:	2222-1751
Date Deposited:	04 Jun 2019 14:42
Last Modified:	01 Oct 2020 12:58
URI:	http://cris.leibniz-zmt.de/id/eprint/1979

Actions (login required)

View Item